How Your Gut Flora Directs Your Immune System

Tue 4th Sep, 2012 - 8:20am by Emma Cockrell

In an Interview with Dr Mercola, Dr. Natasha Campbel McBride talks about how gut ecology can affect the immune system. An excerpt of this interview is below. This is of course, central to Nutritionhelp’s approach in working with clients. In establishing correct gut ecology all of health may be supported. For advice and recommendations to support your own gut ecology take a Nutritionhelp questionnaire, or contact me at info@nutritionhelp.com

There are two primary “arms” in your immune system:

1. Th1 immunity is responsible for normal reactions to anything in your environment, from pollen to animal dandruff, dust mites, chemicals, food and anything else you come into contact with. Th1 is kept robust and healthy by your gut flora. As long as your gut flora is normal, you will have no adverse symptoms when exposed to these types of environmental influences, but if your gut flora is abnormal, your Th1 become increasingly disabled
2. Th2 immunity is designed to address immune functions inside your body, and is not equipped to handle environmental influences. However, it will try to compensate if your Th1 becomes disabled. Unfortunately, since it’s not properly equipped for this job, it ends up dealing with environmental influences like pollen and foods in an inappropriate way; the end result of which is allergies and intolerances.

It’s important to realize that food allergies and intolerances are a very different group of allergies from the more acute anaphylactic allergies. Food intolerances caused by disabled Th1 (due to abnormal gut flora) are not mediated by the same immunoglobulin as the true allergies are. Food intolerances can also manifest hours, days, or even weeks later, making identifying food allergies very difficult.

 “Different reactions can also overlap on top of each other. For example, on any given day you can be reacting to broccoli that you have just had for lunch, and to lamb that you’ve eaten yesterday, and to egg that you’ve eaten two days ago, and to a piece of bread that you’ve eaten 10 days ago. All of these reactions overlap on top of each other. On any given day, you have no idea what exactly you’re reacting to,” Dr. McBride explains.

Making matters even more difficult, these food allergies and intolerances can result in all sorts of reactions, from headache, to sneezing, to rashes, or abdominal pains or swollen joints. Or they may result in psoriasis, or cause eczema to flare up.

“Or, it can be an episode of depression, anxiety, or a panic attack. Any kind of symptom can be brought up by food allergies and intolerances,” Dr. McBride says.

At the same time, because your gut flora is abnormal, your gut lining begins to deteriorate, since it is actively maintained by our gut flora. (The beneficial bacteria in your gut make sure the cells that line your entire digestive tract are healthy, well-fed, and protected from chemical- or microbial attacks.) As your gut lining deteriorates, the junctions between the cells open up, causing your gut to become porous, or “leaky.”

“It becomes like a sieve, and foods don’t get the chance to be digested properly before they are absorbed,” Dr. McBride explains.

“They’re absorbed in this maldigested or partially broken down form. When the immune system and the bloodstream finds them and looks at them, it doesn’t recognize them as food. It says, “You’re not food. I don’t recognize you,” and it reacts to them. It creates immune complexes, which attack these partially digested proteins. As a result, we’ll get all sorts of symptoms in your body.”

The answer to this scenario is to encourage the integrity of the gut lining.  A major factor in this will be to rebalance yeasts and pathogens within the gut with friendly bacteria. Visit www.nutritionhelp.com for more information on Nutritionhelp’s approach to support gut ecology.